The federal opposition has called for a national review to determine why Australia's road toll is again on the rise.
Labor transport spokesman Anthony Albanese says the government must look into why, after years of decline, the nation's road toll has increased in recent years.
More than 20 people have died on NSW roads alone during the Christmas period, while five have been killed in Queensland and more than 10 in Victoria.
Mr Albanese says the government must take urgent measures.
"The government needs to have an urgent reassessment of why it is that more people are dying on our roads with tragic consequences for their families and for their communities," he told reporters in Sydney on Thursday.
"This needs an explanation and it needs a strategy of how we can return to a declining road toll."
His comments came as Australian actress Jessica Falkholt remained in a critical condition in hospital two days after a fiery crash on the NSW south coast.
Ms Falkholt's parents were killed in the crash near Ulladulla on Boxing day and her 21-year-old sister Annabelle was also critically injured.
The accident brought the number of people killed on NSW roads since December 15 to 22.
Both NSW and Victorian police say regional areas of each state are over-represented in figures.
In NSW, 285 people have died on regional roads this year compared with 103 in metropolitan areas.
Police blame the disparity on poor decisions by drivers, including speeding, drink driving and fatigue and Assistant NSW Commissioner Michael Corboy says road users need to take more responsibility.
"Tragically, when a bad decision is made by a driver or rider, it is not only that person that is put at risk, they are usually putting their own passengers and all other road users at risk of getting involved in a fatal crash," he said in a statement.
"We are past the point of being disappointed, we are now angry that drivers are not listening to our warnings."
Federal Transport Minister Barnaby Joyce has been contacted for comment.